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How Does ADHD Medication Work? The drugs help reduce ADHD symptoms by increasing levels dopamine and Noradrenaline, which are chemicals that transmit messages between brain cells. The most frequently prescribed stimulants are methylphenidate atomoxetine and glycine. Finding the right dosage and medication will require a lot of trial and error. Communication with your doctor should be honest and open. Stimulants The stimulant medications prescribed to treat ADHD increase levels of dopamine and naradrenaline
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