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3 (P0.001). The risk of ischemic events increased with increasing USR score (P for trend 0.001). The C statistic of the USR score was 0.84 in the derivation sample and 0.82 in the validation sample. The USR score to assess the risk of ischemic events in patients with carotid stenosis showed preferable discrimination ability and robustness. While external validation is warranted to prove the predictive value, this risk score could help accelerate triage decisions in similar patient populations. The USR score to assess the risk of