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ADHD OTC Medication Most children and adults who use ADHD medication will experience some adverse side effects. They typically include weight loss as well as stomach upsets and changes in heart rate. Healthy eating and enough sleep can minimize these side effects. Stimulants boost the communication between brain cells, assisting children focus and manage impulses. They can also cause tics or increase blood pressure. These are controlled substances that can be crushed or snorted to produc