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https://www.selleckchem.com/pr....oducts/Sapogenins-gl
novel sarcolemmal background Ca2+ influx via the TRPC6 channel is responsible for SR Ca2+ overload and Ca2+ waves. The increased propensity for Ca2+ waves in heart failure results from an increase of background influx, and a lower threshold SR content. The results of the present study highlight a novel mechanism by which Ca2+ waves may arise in heart failure, providing a basis for future work and novel therapeutic targets.Withdrawal C Varesio et al., Parenteral Nutrition in a GLUT1DS Patient Following Classic Ketogenic Die

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