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There were 117 in-hospital deaths, representing an 8.5% mortality rate for the state of São Paulo during the last decade. Whereas highest volume organizations (6 radical cystectomies/year) had a mortality rate of 6.1%, the lowest volume (1 radical cystectomy /year) had a 17.5% in-hospital mortality rate. There was a strong relation between organization volume of radical cystectomy and in-hospital mortality rate after radical cystectomy in São Paulo from 2008-2018. Unfortunately, we could not observe a trend toward centralization o