https://www.selleckchem.com/pr....oducts/gsk1070916.ht
Step 1 showed a negligible bias of the PK model to underpredict concentrations (-0.84 mg/L). Step 2 revealed a high level of agreement between risk of target non-attainment predictions for creatinine clearances 50 mL/min (CCC = 0.99, but considerable deviations for patients 50 mL/min. For 27% of EUCAST-listed pathogens the median cumulative-fraction-of-response for the observed patients receiving standard dosing was 90%. The MeroRisk-calculator was successfully evaluated For patients with maintained renal function it a
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