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Further work is needed to better understand the physiological and functional consequences of noise-induced vestibular impairment in animals and humans.Objectives Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis and sporadic Creutzfeldt-Jakob disease (sCJD) share similar clinical features. Here, we present two unusual cases of anti-NMDAR encephalitis who were misdiagnosed as sCJD at first. Methods We described two patients' clinical manifestations, as well as the string of symptomatological evolution, treatments, and follow-up resul