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ADHD and Sleep Medication People suffering from ADHD struggle to get sleep. They are restless when they finally get to sleep, and a lot wake up frequently throughout the night. Actigraphy and polysomnography, both of which are measures that are objective, show that children with ADHD are more tired and have less efficient sleep than their control counterparts. However the sleep quality measures that are objective improve by methylphenidate (MPH) treatment. 1. Restlessness medication to calm nerves ADHD can make it difficult to sleep well. Many people who suffer f