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ADHD Medication - Ritalin (Methylphenidate) Ritalin (methylphenidate) increases two brain chemicals that control the ability to move and focus. It is one of the most common drugs for children suffering from ADHD. It also helps adults concentrate better and be less fidgety. Certain people mix Ritalin with other ADHD treatment, such as behavioral therapy. Certain medications can cause problems. For example, people shouldn't take it with monoamine oxidase inhibitors such as isocarboxazid,