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Finding the Best Medication For ADHD The most common medication prescribed for ADHD is stimulants. They include amphetamines and methylphenidates. Short-acting stimulants start working in less than an hour and need to be taken multiple times per day. Long-acting stimulations last up to 16 hours and are taken at least once a day. Your doctor may prescribe antidepressants, or other medications "off-label" to treat ADHD symptoms. are approved to treat d

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