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Our DIC assay protocol ended up being further enhanced by now relying on the concept of the no observable adverse impact level (NOAEL) for identifying the greatest test compound focus corresponding to a DICI ≥ 0.78. Expected protection margin values were consequently determined for compounds displaying hepatotoxic and/or cholestatic impacts in customers, hence enabling analysis for the overall performance of your DIC assay. Of note, this assay are extended to explore the role of medicine metabolites in

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