https://www.selleckchem.com/pr....oducts/chir-99021-ct
The Cell Counting kit-8 (CCK8) assay was performed to detect cell viability. The expression level of a microglia marker (CD11b) was detected by immunofluorescence. The mRNA and protein expression levels of BGN and Toll-like receptor 2 (TLR2) were determined by quantitative RT-PCR and western blotting. BGN was upregulated in activated microglial cells. Knockdown of BGN efficiently attenuated β-amyloid-induced microglial activation and expressions of proinflammatory factors. Furthermore, the present findings provided eviden
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