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The antibodies produced showed high opsonic activity against clinically isolated GAS strains D3840 and GC2 203. The use of the CPP-liposome delivery system is a promising strategy for liposome-based GAS vaccine development.(1) Objective Sleep problems have become one of the current serious public health issues. The purpose of this research was to construct an ideal pressure distribution model for head and neck support through research on the partitioned support surface of a pillow in order to guide the development of ergonomic pillows.