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These include versican cleavage by ADAMTS9 that will be necessary for interdigital internet regression during limb development, ADAMTS5-mediated aggrecan degradation in osteoarthritis leading to shared erosion, and mutations in ADAMTS10 or ADAMTS17 that cause Weill-Marchesani problem, a short stature problem with bone tissue, shared, muscle, cardiac, and eye involvement. Because the function of ADAMTS proteases and proteases generally speaking is mostly define

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