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The key steps of this synthesis consist of an organocatalytic asymmetric Diels-Alder reaction , a diastereoselective intramolecular aza-Michael response, and an intramolecular SN2 cyclization to make multisubstituted nitrogen-containing heterocycles. In addition, our complete synthesis resulted in the stereochemical reassignment in the decahydroquinoline band of senepodine F. Complete artificial heart (TAH) implantation

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