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Finding For Adults Stimulants like methylphenidate (Ritalin) or amphetamine (Vyvanse) are effective to increase and regulate levels of brain chemicals. These drugs can lead to a loss of appetite, sleep problems as well as weight fluctuations and tics in certain people. Atomoxetine, along with certain antidepressants, such as bupropion, are all non-stimulants which work slowly to treat ADHD symptoms. boost