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EGFR amplification was commonly detected in patients with acquired lcotinib/gefitinib resistance. DNMT3A and NOTCH4 mutations may be associated with the benefit of icotinib/gefitinib treatment.This paper investigates the influence of a known cue on the oblique effect in orientation identification and explains how subjects integrate cue information to identify target orientations. We design the psychophysical task in which subjects estimate target orientations in the presence of a known oriented reference line. For comparison the control
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