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es and may vary from jurisdiction to jurisdiction. Penile cancer is a rare disease with significant morbidity. Because of the low volume of cases, it has been suggested that its treatment should be centralized in order to improve outcomes through better management of both the primary tumor and distant disease. We reviewed and summarized the most relevant recent publications regarding centralization of penile cancer management. Management of penile cancer in academic and supra-regional centers was associated with better survival outcomes.

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