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Crohn's disease is a chronic and unpredictable inflammatory bowel disease that leads to important psychosocial difficulties especially during sensitive developmental stages such as childhood and adolescence. While risk factors for mood disorders have been identified in the literature, those for quality of life and psychosocial functioning have not. This systematic review explored the determinants of quality of life and psychosocial adjustment to pediatric Crohn's disease. Four international databases were consulted in March 2020 PubMed
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