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ADHD Stimulant Medication Stimulants aid in the treatment of 70 percent to 80% adults and children with ADHD. They reduce symptoms by increasing dopamine and norepinephrine levels. These medicines begin working within 30 to 45 minutes and last between 3 and 6 hours. They are available in liquid form or chewable tablets. Nonstimulant drugs may be prescribed by your physician to complement stimulants. These include atomoxetine as well as guanfacine.

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