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1% (404 of 791), which was significantly higher (P0.01) than in small clinics with less than two veterinary practitioners (34.0%, 154 of 453). In the antibiogram study, the susceptibility rates of oxacillin (MPIPC, 61.5%), cefpodoxime (CPDX, 55.8%) and minocycline (MINO, 55.8%) were significantly higher in 2019 (n=52) than in 2017 to 2018 (n=54; MPIPC, 37.0%; CPDX, 33.3%; MINO, 20.4%; P0.05). Hospital size could affect the isolation rate of MRSP in dogs. Restricted use of antimicrobials for over a year based on cumulative antibio