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https://www.selleckchem.com/products/GDC-0449.html
The downregulated tricellulin expression in active UC was recovered in remission UC to control values. Likewise, angulins were in remission UC at the same levels as in controls. Also, the epithelial resistance which was decreased in active UC was restored in remission to the same range as in controls, along with the unaltered paracellular permeabilities for fluorescein and FITC-dextran 4kDa. In remission of UC, tricellulin expression level as well as intestinal barrier functions were restored to normal, after they were impaired in acti

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