https://www.selleckchem.com/pr....oducts/stf-083010.ht
FLVCR1 knockdown inhibited cell proliferation and colony formation ability, induced cell apoptosis, and repressed cell migration and invasion of ESCC . Inhibition of FLVCR1 markedly repressed tumorigenicity and metastasis of ESCC cells . Mechanistically, chromosome segregation 1-like (CSE1L) was identified to interact with FLVCR1 using a Co-IP assay. Moreover, the inhibitory effect of FLVCR1 knockdown on proliferation and migration was counteracted by the exogenous expression of CSE1L. FLVCR1 plays a pivotal role in ESCC cell surviva
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