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How to Choose the Best ADHD Medication for Adults The stimulant drugs like methylphenidate and amphetamine work by boosting and balancing the levels of brain chemicals. Doctors typically prescribe them as pills, liquid or patches. Healthcare professionals also use medications known as norepinephrine reuptake inhibitors and alpha-2 agonists to treat ADHD. These are usually used "off-label" for this purpose, since they're FDA-approved to treat other conditions. Stimulants Stimulants are among the most frequently prescribed ADHD medication for ADHD. in
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