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To combine evidence on andexanet alfa and prothrombin complex concentrates for factor Xa inhibitor-associated bleeding to guide clinicians on reversal strategies. Embase, Pubmed, Web of Science, and the Cochrane Library. Observational studies and randomized clinical trials studying hemostatic effectiveness of andexanet alfa or prothrombin complex concentrate for acute reversal of factor Xa inhibitor-associated hemorrhage. Two independent reviewers extracted the data from the studies. Visualization and comparison of hemostatic effectiven
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