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Does ADHD Medication Work? When someone receives a prescription for ADHD medication, they frequently be concerned about whether the medication will work and how long it will last. Here are some easy answers. Stimulants work by adjusting levels of brain chemicals that send messages about attention and activity. Norepinephrine, dopamine and other brain chemicals are included. They are often considered to be the first-line treatment option for adults suffering from ADHD. 1. Stimulants Stimulants are often used to tr
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