https://gefitinib-basedprotac3.....com/12-surfaces-pho
We recently identified a cellular framework labeled as the mitochondrial-derived area (MDC) that is created from mitochondria in response to amino acid overabundance tension. Just how cells form MDCs is unclear. Here, we show that MDCs are dynamic structures that form and stably persist at sites of contact amongst the ER and mitochondria. MDC biogenesis calls for the ER-mitochondria encounter framework (ERMES) as well as the conserved GTPase Gem1, facets formerly implicated in lipid change and mem
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