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Finding the Best Medication For ADHD There are a variety of ADHD medications available, and it can take some time to find the one that works best for you. It's important to be honest with your doctor about how ADHD affects you so they can prescribe the best medication for you. Stimulants are among the most frequently used medications for ADHD however, they can trigger negative side effects, such as changes in mood and anxiety. Some people also experience tics when taking stimulants. Methylphenidate Methylphenidate, the most common medication for ADHD, is used by