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Patients had a baseline Hamilton Ranking Scale for depression rating of at the very least 18. Patients were allotted in a random trend, 23 to fluoxetine 40 mg/day plus modafinil 400 mg/day (200 mg bid) (morning and evening) and 23 to fluoxetine 40 mg/day plus placebo. Hamilton Score Scale rating for Depression over the trial period. Lots of the questions on the Modified Fatigue Influence Scale (scores 45 on the MFIS were used to outline fatigue) are affected by depression, c