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immune checkpoint inhibitors(ICIs) have shown contradictory results in patients with advanced gastro-oesophageal junction/gastric cancer(GOJ/GC). to identify specific patient subgroups that would derive survival benefit from ICIs. a subgroup meta-analysis of randomised clinical trials(RCTs) was carried out. four phase-III-RCTs were identified with data on the following variables primary location(Gastric vs GOJ); age(≤ 65 vs 65); gender(male vs female); ECOG PS(0 vs 1); ethnicity (Asian vs non-Asian), histology(intestinal vs diffuse), P