https://www.selleckchem.com/pr....oducts/cilengitide-e
BACKGROUND Recent studies indicate that standard doses of hypnotics reduce or do not change the apnea-hypopnea index (AHI) or pharyngeal muscle activity. A 1-month trial of nightly zopiclone (7.5mg) modestly reduced the AHI versus baseline without changing other sleep parameters or next-day sleepiness. RESEARCH QUESTION This study aimed to determine the effects of high-dose zopiclone (15mg) on AHI, arousal threshold, genioglossus muscle responsiveness and next-day alertness in selected people with obstructive s
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