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Finding the Best ADHD Medication For Adults Stimulants like methylphenidate or amphetamine, (Vyvanse), quickly work to regulate brain chemicals. These medications can cause loss of appetite, sleep problems and weight changes, as well as tics in some people. Atomoxetine and some antidepressants (like bupropion) are non-stimulant drugs that work slowly to assist with ADHD symptoms. They increase a chemical within the brain called norepinephrine to improve concentration and control impulses. Stimulants
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