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Among those are mutations in miR-140 and miR-17~92 miRNAs which cause skeletal dysplasias. We additionally discuss pathological mechanisms underlining these skeletal dysplasias.Bone metastases are typical in breast cancer that can cause significant morbidity including fractures, extreme discomfort, nerve compression and hypercalcaemia. Alongside developments in the multidisciplinary administration for clients with metastatic breast cancer, the use of bisphosphonates, and much m

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