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001), and open fracture (OR 6.6, 95% CI 3.7-11.7, p0.001), were associated with a significantly higher SSI risk. Analysis of microbial sensitivity tests revealed that 55.1% of the pathogens were resistant to perioperative antibiotic prophylaxis (PAP). Most of the identified risk factors cannot be controlled or are subject to other factors that are difficult to control. However, our data suggest that the choice of PAP may influence the rate of SSI. This possibility should be investigated in a prospective randomized controlled trial.
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