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Rationale The primary aims of this study were to determine the correlation between absolute quantitative 99mTc-pyrophosphate (99mTc-PYP) metrics and traditional measures of cardiac amyloid burden and to measure intra-observer repeatability of the quantitative metrics. Methods We studied 72 patients who underwent 99mTc-PYP SPECT/CT using a novel general purpose CZT-based SPECT/CT system (Veriton, Spectrum Dynamics Inc). The clinical standard for these studies is visual grading (0-3 myocardial uptake none, 0.324 on LVMI; the largest standa
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