https://www.selleckchem.com/pr....oducts/dir-cy7-dic18
Per pharmacokinetic studies in rats, a burst phase in the plasma concentration-time curve was observed after intramuscular injection in the first 2 h followed by a clear zero-order release phase. Overall, brexpiprazole achieved sustained release from PLGA microspheres for up to 40 days. A PLGA microsphere loaded with brexpiprazole was successfully developed and demonstrated potential for extended-release of therapeutics for schizophrenia treatment. A PLGA microsphere loaded with brexpiprazole was successfully developed and demonst
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