https://www.selleckchem.com/pr....oducts/kaempferide.h
Type 1 diabetes (T1D) is an autoimmune disease caused by the destruction of pancreatic β-cells producing insulin. Both T1D patients and animal models exhibit gut microbiota and mucosa alterations, although the exact cause for these remains poorly understood. We investigated the production of key cytokines controlling gut integrity, the abundance of segmented filamentous bacteria (SF involved in the production of these cytokines, and the respective role of autoimmune inflammation and hyperglycaemia. We used several mouse models of
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