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© 2020 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim.Platelet concentrates have emerged as innovative autologous blood products that enhance tissue healing and regeneration in regenerative therapy. A common feature of these products is their higher than baseline platelet concentration, which improves wound healing and tissue repair. Four main categories of products can be easily defined, based on their leukocyte content and fibrin architecture pure platelet-rich plasma, such as Cell Separator PRP or Anitua' PRGF; leukocyte- and platel