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The both trough level and AUC had been considerable threat elements for the event of vancomycin induced-nephrotoxicity (p0.001, p=0.001). The exposure-response analysis uncovered that the trough amount of 15μg/mL had been connected with 12.0% nephrotoxicity occurrence and AUC of 600 was related to 12.9% nephrotoxicity incidence. Throughout the treatment, 90 clients had an initial trough concentration of ≥15μg/mL, and 124 patients had AUC of ≥600μgh/mL. The multiple logistic regression anal

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