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Hereditary difference plays a part in initiation, regular smoking, nicotine dependence, and cessation. We present a Fagerström Test for Nicotine Dependence (FTND)-based genome-wide organization study in 58,000 European or African ancestry smokers. We observe five genome-wide considerable loci, including formerly unreported loci MAGI2/GNAI1 (rs271470 and TENM2 (rs1862416), and extend loci reported for any other smoking faculties to nicotine reliance. Utilizing the heavin
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