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The result of the sequential trial, the time to achieve proper sedation, the analepsia time and the adverse effects were recorded. Results All the 50 patients went through bronchoscopy completely. The regression function of the sequential trial was Y=12.589+16.593X, the ED50 and the ED95 of remimazolam tosilate were 0.174 (95%CI 0.162-0.186) mg/kg and 0.219 (95%CI 0.199-0.312) mg/kg, respectively. The time to achieve proper sedation was (50±11) s and the mean analepsia time after the use of flumazenil was (56±16) s. There was one patient with resp

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