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(3) Aerotropolis must continuously optimize AIC's internal synergetic development mechanism and coordinate the relationship between AIC system and the regional environment. Generativity is a process whereby patients nearing the end of life invest in those they will soon leave behind. In recent years, the trajectory of cancer has changed, as new therapies have prolonged survival and patients often live with metastatic disease for several years. For these patients and for the healthcare professionals who care for them it can be useful to

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