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Finally, the combination of both siRNA and GCs in the same carrier allowed for the same cell to target both the GCs receptor as well as any other signaling pathway involved in RA. Nanomedicines appear to be very promising for the delivery of conventional and novel drugs in RA therapeutics. This article is categorized under Therapeutic Approaches and Drug Discovery Emerging Technologies Biology-Inspired Nanomaterials Nucleic Acid-Based Structures. © 2020 Wiley Periodicals, Inc.OBJECTIVES To present our experience with ammonium

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