https://alisertibinhibitor.com..../?p=12438preview=tru
Through RNA pull-down, RNA immunoprecipitation, and protein synthesis assay, the mechanism of YTHDF1 regulating Foxm1 was investigated. Following, Foxm1 had been inhibited by thiostrepton, and mobile expansion was recognized. In vivo, mice obtained a tail vein injection of adenovirus containing si-YTHDF1 and were exposed to hypoxia therapy. Pulmonary vascular changes, right ventricular systolic force (RVSP), and genetics involving expansion were reviewed. YTHDF1 silencing reduced more hypoxic PASMC proliferation and Foxm1 protein
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