https://www.selleckchem.com/pr....oducts/alantolactone
Finally, G12/13-induced myosin phosphatase target subunit 1 (MYPT1) phosphorylation was inhibited by AG17, confirming that Pyk2 regulates RhoA/p160ROCK activation in platelets. These results demonstrate that Pyk2 downstream of G12/13 pathways regulates platelet shape change as well as platelet aggregation and dense granule secretion through the regulation of RhoA/p160ROCK. A growing number of evidence shows that human-associated microbiota is an important contributor in health and disease. However, much of the complexity of host-m
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