https://www.selleckchem.com/pr....oducts/sch-527123.ht
However, restoring sirtuin 1 by RESV administration significantly blocked the BPA-induced decrease in NBS1 and subsequently attenuated the BPA-induced impairment of DNA repair and apoptosis, as indicated by phosphorylated H2AX expression and staining and PARP expression. Moreover, RESV administration significantly ameliorated BPA-aggravated NOD-like receptor pyrin domain 3 and caspase 1 activation and interleukin-1β production, which were abolished by NBS1 knockdown. Furthermore, RESV administration prevented BPA-induced aggravation
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