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The changes in DPPH radical-scavenging capability of catechin and epicatechin during 24 h incubation with fecal microbiota in vitro and the targeted analysis of the characteristic metabolites by using UPLC-Q-TOF indicated that increase in antioxidant activity was synchronous with the accumulation of C-ring cleavage metabolites. Therefore, C-ring cleavage metabolite, 1-(3',4'-Dihydroxyphenyl)-3-(2'',4'',6''-trihydroxyphenyl)propan-2-ol (3,4-DHPP-2-ol), was separated from incubation liquid. The antioxidant activities of this metabolite an
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