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The pooled SNPs of AMBN showed associations with caries (OR 0.45; 95%CI 0.29-0.72). The pooled polymorphisms of AMELX were associated with caries experience (OR 1.78; 95%CI 1.23-2.56). In the analysis of the homozygous genotype, no SNP showed a significant association. Egger's test showed no significant publication bias for all models (p 0.05). The present findings showed that the genes TFIP11, AMBN, and AMELX play an important role in dental caries. Several single nucleotide polymorphisms related to the genes in the formation of