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ADHD Medication - Stimulants Stimulants alter the way that the brain releases chemicals that affect focus. begin stimulants for ADHD patients and gradually increase the dose until they can help. People who suffer from ADHD also take antidepressants (they're not just for depression). These drugs work on the same chemicals as stimulants but have less adverse negative effects. Stimulants Stimulants are among the first medications doctors usually prescribe for ADHD. They boost levels of dopam