https://go6976inhibitor.com/an....-all-inclusive-evalu
Right here, we engineered an antibody, termed LK30, that binds into the extracellular area for the aGPCR ADGRL3, and particularly will act as an agonist for ADGRL3 but not for its isoform, ADGRL1. The LK30/ADGRL3 complex structure unveiled that the LK30 binding site on ADGRL3 overlaps aided by the binding website for an ADGRL3 ligand - teneurin. In cellular-adhesion assays, LK30 especially smashed the trans-cellular interaction of ADGRL3 with teneurin, although not with another ADGR
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